Latest Palo Alto Investors LP Stock Portfolio
Palo Alto Investors LP Performance:
2024 Q3: -0.84%YTD: -8.18%2023: -7.95%
Performance for 2024 Q3 is -0.84%, and YTD is -8.18%, and 2023 is -7.95%.
About Palo Alto Investors LP and 13F Hedge Fund Stock Holdings
Palo Alto Investors LP is a hedge fund based in PALO ALTO, CA. On 02-Jun-2023, the fund reported that it had an AUM (Regulated Assets under Management) of $1.3 Billions. In it's latest 13F Holdings report, Palo Alto Investors LP reported an equity portfolio of $769.9 Millions as of 30 Sep, 2024.
The top stock holdings of Palo Alto Investors LP are INSM, FOLD, BMRN. The fund has invested 18.4% of it's portfolio in INSMED INC and 11.3% of portfolio in AMICUS THERAPEUTICS INC.
The fund managers got completely rid off CYTOKINETICS INC (CYTK) stocks. They significantly reduced their stock positions in BLUEBIRD BIO INC, REVANCE THERAPEUTICS INC (RVNC) and UNITED THERAPEUTICS CORP (UTHR). Palo Alto Investors LP opened new stock positions in ALNYLAM PHARMACEUTICALS INC (ALNY), PTC THERAPEUTICS INC (PTCT) and BIONTECH SE-ADR. The fund showed a lot of confidence in some stocks as they added substantially to IOVANCE BIOTHERAPEUTICS INC (IOVA), NOVOCURE LTD (NVCR) and ANAPTYSBIO INC (ANAB).
The top stock holdings of Palo Alto Investors LP are INSM, FOLD, BMRN. The fund has invested 18.4% of it's portfolio in INSMED INC and 11.3% of portfolio in AMICUS THERAPEUTICS INC.
The fund managers got completely rid off CYTOKINETICS INC (CYTK) stocks. They significantly reduced their stock positions in BLUEBIRD BIO INC, REVANCE THERAPEUTICS INC (RVNC) and UNITED THERAPEUTICS CORP (UTHR). Palo Alto Investors LP opened new stock positions in ALNYLAM PHARMACEUTICALS INC (ALNY), PTC THERAPEUTICS INC (PTCT) and BIONTECH SE-ADR. The fund showed a lot of confidence in some stocks as they added substantially to IOVANCE BIOTHERAPEUTICS INC (IOVA), NOVOCURE LTD (NVCR) and ANAPTYSBIO INC (ANAB).
Palo Alto Investors LP Annual Return Estimates Vs S&P 500
Our best estimate is that Palo Alto Investors LP made a return of -0.84% in the last quarter. In trailing 12 months, it's portfolio return was -2.65%.
New Buys
| Ticker | $ Bought |
|---|---|
| alnylam pharmaceuticals inc | 38,691,500 |
| ptc therapeutics inc | 9,811,800 |
| biontech se-adr | 2,993,720 |
| edwards lifesciences corp | 2,604,820 |
| bicycle therapeutics plc-adr | 1,348,340 |
| instil bio inc | 751,628 |
| pyxis oncology inc | 623,900 |
| abeona therapeutics inc | 81,307 |
New stocks bought by Palo Alto Investors LP
Additions
| Ticker | % Inc. |
|---|---|
| iovance biotherapeutics inc | 43.72 |
| novocure ltd | 5.63 |
| anaptysbio inc | 5.02 |
| acelyrin inc | 4.53 |
| acadia pharmaceuticals inc | 4.35 |
| prothena corp plc | 4.3 |
| sarepta therapeutics inc | 4.25 |
Additions to existing portfolio by Palo Alto Investors LP
Reductions
| Ticker | % Reduced |
|---|---|
| bluebird bio inc | -86.96 |
| revance therapeutics inc | -69.34 |
| united therapeutics corp | -31.35 |
| elevation oncology inc | -27.89 |
| alkermes plc | -22.38 |
| staar surgical co | -20.99 |
| biogen inc | -20.8 |
| amicus therapeutics inc | -9.8 |
Palo Alto Investors LP reduced stake in above stock
Sold off
| Ticker | $ Sold |
|---|---|
| alnylam pharmaceuticals inc | -44,498,900 |
| cytokinetics inc | -6,052,830 |
Palo Alto Investors LP got rid off the above stocks
Sector Distribution
Palo Alto Investors LP has about 97.2% of it's holdings in Healthcare sector.
| Sector | % |
|---|---|
| Healthcare | 97.2 |
| Others | 1.6 |
| Financial Services | 1.2 |
Market Cap. Distribution
Palo Alto Investors LP has about 52.8% of it's portfolio invested in the large-cap and mega-cap stocks.
| Category | % |
|---|---|
| LARGE-CAP | 52.8 |
| MID-CAP | 23.9 |
| SMALL-CAP | 18.1 |
| MICRO-CAP | 3.5 |
| UNALLOCATED | 1.6 |
Stocks belong to which Index?
About 68.4% of the stocks held by Palo Alto Investors LP either belong to S&P 500 or RUSSELL 2000 index.
| Index | % |
|---|---|
| RUSSELL 2000 | 60.9 |
| Others | 31.6 |
| S&P 500 | 7.5 |
Palo Alto Investors LP Holdings Map
This heatmap illustrates the top 50 positions within the fund's portfolio.
Current Stock Holdings of Palo Alto Investors LP
Palo Alto Investors LP has 45 stocks in it's portfolio. About 76.8% of the portfolio is in top 10 stocks. STAA proved to be the most loss making stock for the portfolio. RVNC was the most profitable stock for Palo Alto Investors LP last quarter.
Last Reported on: 14 Nov, 2024| Ticker | Namesorted ascending | % Portfolio | Shares Held | $ Value | Type | % Change | Options | |
|---|---|---|---|---|---|---|---|---|
| ABEO | abeona therapeutics inc | 0.01 | 12,865 | 81,307 | new | |||
| ACAD | acadia pharmaceuticals inc | 5.04 | 2,523,960 | 38,818,400 | added | 4.35 | ||
| ACRS | aclaris therapeutics inc | 0.09 | 569,832 | 655,307 | unchanged | 0.00 | ||
| ALDX | aldeyra therapeutics inc | 0.16 | 225,465 | 1,215,260 | unchanged | 0.00 | ||
| ALGN | align technology inc | 1.25 | 37,772 | 9,606,180 | unchanged | 0.00 | ||
| ALKS | alkermes plc | 1.40 | 384,656 | 10,766,500 | reduced | -22.38 | ||
| ALNY | alnylam pharmaceuticals inc | 5.03 | 140,681 | 38,691,500 | new | |||
| ALNY | alnylam pharmaceuticals inc | 0.00 | 0.00 | 0.00 | sold off | -100 | ||
| ANAB | anaptysbio inc | 3.67 | 843,971 | 28,273,000 | added | 5.02 | ||
| BCYC | bicycle therapeutics plc-adr | 0.17 | 59,582 | 1,348,340 | new | |||
| BIIB | biogen inc | 5.76 | 228,916 | 44,373,100 | reduced | -20.8 | ||
| BMRN | biomarin pharmaceutical inc | 9.95 | 1,090,060 | 76,620,000 | reduced | -3.55 | ||
| CYTK | cytokinetics inc | 0.00 | 0.00 | 0.00 | sold off | -100 | ||
| EHTH | ehealth inc | 1.24 | 2,347,520 | 9,577,880 | reduced | -0.11 | ||
| ELEV | elevation oncology inc | 0.10 | 1,298,100 | 778,728 | reduced | -27.89 | ||
| EW | edwards lifesciences corp | 0.34 | 39,473 | 2,604,820 | new | |||
| FOLD | amicus therapeutics inc | 11.30 | 8,145,310 | 86,991,900 | reduced | -9.8 | ||
| GBIO | generation bio co | 0.05 | 150,475 | 371,673 | unchanged | 0.00 | ||
| GOSS | gossamer bio inc | 0.80 | 6,277,090 | 6,191,720 | unchanged | 0.00 | ||
| HUM | humana inc | 0.16 | 3,985 | 1,262,210 | unchanged | 0.00 | ||