Latest Palo Alto Investors LP Stock Portfolio
$886Million
Equity Portfolio Value
Last Reported on: 15 May, 2024
About Palo Alto Investors LP and it’s 13F Hedge Fund Stock Holdings
Palo Alto Investors LP is a hedge fund based in PALO ALTO, CA. On 02-Jun-2023, the fund reported that it had an AUM (Regulated Assets under Management) of $1.3 Billions. In it's latest 13F Holdings report, Palo Alto Investors LP reported an equity portfolio of $886.7 Millions as of 31 Mar, 2024.
The top stock holdings of Palo Alto Investors LP are INSM, FOLD, BMRN. The fund has invested 13.5% of it's portfolio in INSMED INC and 12.4% of portfolio in AMICUS THERAPEUTICS INC.
The fund managers got completely rid off VANDA PHARMACEUTICALS INC (VNDA) and SIGHT SCIENCES INC (SGHT) stocks. They significantly reduced their stock positions in UNITED THERAPEUTICS CORP (UTHR), BIOMARIN PHARMACEUTICAL INC (BMRN) and BIOGEN INC (BIIB). Palo Alto Investors LP opened new stock positions in ACELYRIN INC, ELEVATION ONCOLOGY INC (ELEV) and NUVATION BIO INC (NUVB). The fund showed a lot of confidence in some stocks as they added substantially to TAYSHA GENE THERAPIES INC (TSHA), BLUEBIRD BIO INC (BLUE) and ALNYLAM PHARMACEUTICALS INC (ALNY).
The top stock holdings of Palo Alto Investors LP are INSM, FOLD, BMRN. The fund has invested 13.5% of it's portfolio in INSMED INC and 12.4% of portfolio in AMICUS THERAPEUTICS INC.
The fund managers got completely rid off VANDA PHARMACEUTICALS INC (VNDA) and SIGHT SCIENCES INC (SGHT) stocks. They significantly reduced their stock positions in UNITED THERAPEUTICS CORP (UTHR), BIOMARIN PHARMACEUTICAL INC (BMRN) and BIOGEN INC (BIIB). Palo Alto Investors LP opened new stock positions in ACELYRIN INC, ELEVATION ONCOLOGY INC (ELEV) and NUVATION BIO INC (NUVB). The fund showed a lot of confidence in some stocks as they added substantially to TAYSHA GENE THERAPIES INC (TSHA), BLUEBIRD BIO INC (BLUE) and ALNYLAM PHARMACEUTICALS INC (ALNY).
New Buys
| Ticker | $ Bought |
|---|---|
| ACELYRIN INC | 11,577,500 |
| ELEVATION ONCOLOGY INC | 6,908,400 |
| NUVATION BIO INC | 2,812,450 |
| STOKE THERAPEUTICS INC | 1,699,120 |
| HUMANA INC | 1,381,680 |
| ACLARIS THERAPEUTICS INC | 706,592 |
New stocks bought by Palo Alto Investors LP
Additions
| Ticker | % Inc. |
|---|---|
| TAYSHA GENE THERAPIES INC | 53.11 |
| BLUEBIRD BIO INC | 36.81 |
| ALNYLAM PHARMACEUTICALS INC | 18.34 |
| ANAPTYSBIO INC | 16.45 |
| GOSSAMER BIO INC | 7.26 |
| SAGE THERAPEUTICS INC | 1.44 |
| IOVANCE BIOTHERAPEUTICS INC | 0.29 |
| ACADIA PHARMACEUTICALS INC | 0.22 |
Additions to existing portfolio by Palo Alto Investors LP
Reductions
| Ticker | % Reduced |
|---|---|
| UNITED THERAPEUTICS CORP | -32.35 |
| BIOMARIN PHARMACEUTICAL INC | -24.4 |
| BIOGEN INC | -23.78 |
| INSMED INC | -19.75 |
| ALKERMES PLC | -17.87 |
| SYNDAX PHARMACEUTICALS INC | -14.26 |
| ALIGN TECHNOLOGY INC | -11.85 |
| AMICUS THERAPEUTICS INC | -9.93 |
Palo Alto Investors LP reduced stake in above stock
Sold off
| Ticker | $ Sold |
|---|---|
| VANDA PHARMACEUTICALS INC | -1,177,320 |
| SIGHT SCIENCES INC | -896,756 |
Palo Alto Investors LP got rid off the above stocks
Current Stock Holdings of Palo Alto Investors LP
Last Reported on: 15 May, 2024| Ticker | Namesorted ascending | % Portfolio | Shares Held | $ Value | Type | % Change | Options |
|---|---|---|---|---|---|---|---|
| ACAD | ACADIA PHARMACEUTICALS INC | 5.04 | 2,414,940 | 44,652,300 | ADDED | 0.22 | |
| ACRS | ACLARIS THERAPEUTICS INC | 0.08 | 569,832 | 706,592 | NEW | ||
| ALDX | ALDEYRA THERAPEUTICS INC | 0.08 | 225,465 | 737,271 | UNCHANGED | 0.00 | |
| ALGN | ALIGN TECHNOLOGY INC | 1.82 | 49,105 | 16,102,500 | REDUCED | -11.85 | |
| ALKS | ALKERMES PLC | 1.51 | 495,592 | 13,415,700 | REDUCED | -17.87 | |
| ALNY | ALNYLAM PHARMACEUTICALS INC | 3.08 | 182,766 | 27,314,400 | ADDED | 18.34 | |
| ANAB | ANAPTYSBIO INC | 2.03 | 799,906 | 18,013,900 | ADDED | 16.45 | |
| BIIB | BIOGEN INC | 7.05 | 289,958 | 62,523,600 | REDUCED | -23.78 | |
| BLUE | BLUEBIRD BIO INC | 0.66 | 4,560,170 | 5,837,020 | ADDED | 36.81 | |
| BMRN | BIOMARIN PHARMACEUTICAL INC | 11.18 | 1,134,570 | 99,093,300 | REDUCED | -24.4 | |
| CYTK | CYTOKINETICS INC | 0.88 | 111,717 | 7,832,480 | UNCHANGED | 0.00 | |
| EHTH | EHEALTH INC | 1.85 | 2,715,680 | 16,375,600 | REDUCED | -0.87 | |
| ELEV | ELEVATION ONCOLOGY INC | 0.78 | 1,346,670 | 6,908,400 | NEW | ||
| FOLD | AMICUS THERAPEUTICS INC | 12.41 | 9,344,100 | 110,074,000 | REDUCED | -9.93 | |
| GOSS | GOSSAMER BIO INC | 0.85 | 6,391,780 | 7,542,300 | ADDED | 7.26 | |
| HUM | HUMANA INC | 0.16 | 3,985 | 1,381,680 | NEW | ||
| INSM | INSMED INC | 13.53 | 4,423,370 | 120,006,000 | REDUCED | -19.75 | |
| IOVA | IOVANCE BIOTHERAPEUTICS INC | 3.53 | 2,112,810 | 31,311,900 | ADDED | 0.29 | |
| KPTI | KARYOPHARM THERAPEUTICS INC | 0.87 | 5,102,190 | 7,704,310 | UNCHANGED | 0.00 | |
| MIRM | MIRUM PHARMACEUTICALS INC | 0.18 | 64,700 | 1,625,260 | UNCHANGED | 0.00 | |
| NUVB | NUVATION BIO INC | 0.32 | 772,652 | 2,812,450 | NEW | ||
| NVCR | NOVOCURE LTD | 0.99 | 561,908 | 8,782,620 | UNCHANGED | 0.00 | |
| NVRO | NEVRO CORP | 1.22 | 750,371 | 10,835,400 | UNCHANGED | 0.00 | |
| PRTA | PROTHENA CORP PLC | 4.65 | 1,663,450 | 41,203,600 | ADDED | 0.2 | |
| RLMD | RELMADA THERAPEUTICS INC | 0.38 | 732,400 | 3,405,660 | UNCHANGED | 0.00 | |
| RVNC | REVANCE THERAPEUTICS INC | 2.91 | 5,248,000 | 25,820,200 | ADDED | 0.2 | |
| SAGE | SAGE THERAPEUTICS INC | 2.13 | 1,005,780 | 18,848,200 | ADDED | 1.44 | |
| SGHT | SIGHT SCIENCES INC | 0.00 | 0.00 | 0.00 | SOLD OFF | -100 | |
| SNDX | SYNDAX PHARMACEUTICALS INC | 1.09 | 405,193 | 9,643,590 | REDUCED | -14.26 | |
| SRPT | SAREPTA THERAPEUTICS INC | 2.94 | 201,265 | 26,055,800 | ADDED | 0.18 | |
| STAA | STAAR SURGICAL CO | 5.96 | 1,379,590 | 52,810,700 | ADDED | 0.19 | |
| STOK | STOKE THERAPEUTICS INC | 0.19 | 125,861 | 1,699,120 | NEW | ||
| TSHA | TAYSHA GENE THERAPIES INC | 0.26 | 811,268 | 2,328,340 | ADDED | 53.11 | |
| TVTX | TRAVERE THERAPEUTICS INC | 0.10 | 110,719 | 853,643 | UNCHANGED | 0.00 | |
| URGN | UROGEN PHARMA LTD | 0.04 | 24,500 | 367,500 | UNCHANGED | 0.00 | |
| UTHR | UNITED THERAPEUTICS CORP | 6.94 | 267,759 | 61,509,600 | REDUCED | -32.35 | |
| VERV | VERVE THERAPEUTICS INC | 0.86 | 575,817 | 7,646,850 | UNCHANGED | 0.00 | |
| VNDA | VANDA PHARMACEUTICALS INC | 0.00 | 0.00 | 0.00 | SOLD OFF | -100 | |
| VYNE | VYNE THERAPEUTICS INC | 0.15 | 445,434 | 1,367,480 | UNCHANGED | 0.00 | |
| ACELYRIN INC | 1.31 | 1,715,180 | 11,577,500 | NEW |