Latest HighVista Strategies LLC Stock Portfolio

HighVista Strategies LLC Performance:

2024 Q3: 4.49%YTD: 6.69%2023: 9.54%

Performance for 2024 Q3 is 4.49%, and YTD is 6.69%, and 2023 is 9.54%.

About HighVista Strategies LLC and 13F Hedge Fund Stock Holdings

HighVista Strategies LLC is a hedge fund based in BOSTON, MA. On 27-Jun-2023, the fund reported that it had an AUM (Regulated Assets under Management) of $4.9 Billions. In it's latest 13F Holdings report, HighVista Strategies LLC reported an equity portfolio of $290 Millions as of 30 Sep, 2024.

The top stock holdings of HighVista Strategies LLC are DBC, AMZN, PCVX. The fund has invested 11% of it's portfolio in INVESCO DB COMMDY INDX TRCK and 2.1% of portfolio in AMAZON COM INC.

The fund managers got completely rid off EQUITRANS MIDSTREAM CORP (ETRN), CEREVEL THERAPEUTICS HLDNG I (CERE) and META PLATFORMS INC (META) stocks. They significantly reduced their stock positions in INTRA-CELLULAR THERAPIES INC (ITCI), INSMED INC (INSM) and BOOKING HOLDINGS INC (BKNG). HighVista Strategies LLC opened new stock positions in GE VERNOVA INC, AMGEN INC (AMGN) and EDGEWISE THERAPEUTICS INC (EWTX). The fund showed a lot of confidence in some stocks as they added substantially to APELLIS PHARMACEUTICALS INC (APLS), PROTAGONIST THERAPEUTICS INC (PTGX) and PDD HOLDINGS INC (PDD).

HighVista Strategies LLC Annual Return Estimates Vs S&P 500

Our best estimate is that HighVista Strategies LLC made a return of 4.49% in the last quarter. In trailing 12 months, it's portfolio return was 17.45%.

New Buys

Ticker	$ Bought
ge vernova inc	3,748,210
amgen inc	3,254,640
edgewise therapeutics inc	2,371,090
dyne therapeutics inc	2,352,110
autodesk inc	2,066,100
lithia mtrs inc	1,905,840
delta air lines inc del	1,889,390
hewlett packard enterprise c	1,818,890

New stocks bought by HighVista Strategies LLC

Additions

Ticker	% Inc.
apellis pharmaceuticals inc	375
protagonist therapeutics inc	321
pdd holdings inc	213
rhythm pharmaceuticals inc	160
vera therapeutics inc	140
corbus pharmaceuticals hldgs	94.09
amazon com inc	78.92
bridgebio pharma inc	54.93

Additions to existing portfolio by HighVista Strategies LLC

Reductions

Ticker	% Reduced
intra-cellular therapies inc	-69.2
insmed inc	-64.15
booking holdings inc	-52.84
t-mobile us inc	-46.22
adobe inc	-41.94
immatics n.v	-41.48
intuit	-41.13
alnylam pharmaceuticals inc	-40.39

HighVista Strategies LLC reduced stake in above stock

Sold off

Ticker	$ Sold
equitrans midstream corp	-4,023,800
transocean ltd	-1,229,030
cerevel therapeutics hldng i	-3,974,510
tourmaline bio inc	-1,072,480
pfizer inc	-1,687,190
toast inc	-1,244,690
bilibili inc	-723,472
ideaya biosciences inc	-1,434,450

HighVista Strategies LLC got rid off the above stocks

Sector Distribution

HighVista Strategies LLC has about 39.3% of it's holdings in Healthcare sector.

Sector	%
Healthcare	39.3
Others	30.1
Technology	13.4
Consumer Cyclical	5.7
Industrials	2.7
Consumer Defensive	2.4
Communication Services	2.2
Energy	2
Financial Services	1.8

Market Cap. Distribution

HighVista Strategies LLC has about 30.1% of it's portfolio invested in the large-cap and mega-cap stocks.

Category	%
UNALLOCATED	31.2
MID-CAP	23.5
LARGE-CAP	21.7
SMALL-CAP	14
MEGA-CAP	8.4
MICRO-CAP	1.2

Stocks belong to which Index?

About 53.1% of the stocks held by HighVista Strategies LLC either belong to S&P 500 or RUSSELL 2000 index.

Index	%
Others	46.9
RUSSELL 2000	28.1
S&P 500	25

Top 5 Winners (%)		%
VRDN	viridian therapeutics inc	71.0 %
TVTX	travere therapeutics inc	53.4 %
ACLX	arcellx inc	49.3 %
PCVX	vaxcyte inc	48.0 %
TYRA	tyra biosciences inc	47.0 %

Top 5 Winners ($)		$
VRDN	viridian therapeutics inc	1.8 M
PCVX	vaxcyte inc	1.7 M
ACLX	arcellx inc	1.5 M
TVTX	travere therapeutics inc	1.0 M
INSM	insmed inc	0.9 M

Top 5 Losers (%)		%
CRBP	corbus pharmaceuticals hldgs	-59.3 %
APLS	apellis pharmaceuticals inc	-23.6 %
MDGL	madrigal pharmaceuticals inc	-22.5 %
LQDA	liquidia corporation	-14.6 %
MRUS	merus n v	-14.5 %

Top 5 Losers ($)		$
CRBP	corbus pharmaceuticals hldgs	-2.3 M
MRUS	merus n v	-1.0 M
DYN	dyne therapeutics inc	-0.4 M
HES	hess corp	-0.3 M
APLS	apellis pharmaceuticals inc	-0.3 M

HighVista Strategies LLC Holdings Map

This heatmap illustrates the top 50 positions within the fund's portfolio.

Current Stock Holdings of HighVista Strategies LLC

HighVista Strategies LLC has 141 stocks in it's portfolio. About 25.5% of the portfolio is in top 10 stocks. CRBP proved to be the most loss making stock for the portfolio. VRDN was the most profitable stock for HighVista Strategies LLC last quarter.

Last Reported on: 14 Nov, 2024

Ticker	Namesorted ascending	% Portfolio	Shares Held	$ Value	Type	% Change
ACAD	acadia pharmaceuticals inc	0.13	25,287	388,914	reduced	-2.28

ACI	albertsons cos inc	1.20	188,753	3,488,160	unchanged	0.00

ACLX	arcellx inc	1.59	55,139	4,604,660	added	8.03

ADBE	adobe inc	0.32	1,800	932,004	reduced	-41.94

ADSK	autodesk inc	0.71	7,500	2,066,100	new

AFK	vaneck etf trust	0.58	42,000	1,672,440	reduced	-9.09

AGLE	spyre therapeutics inc	1.07	105,351	3,098,370	reduced	-7.22

ALNY	alnylam pharmaceuticals inc	0.15	1,551	426,572	reduced	-40.39

ALV	autoliv inc	0.23	7,200	672,264	new

AMD	advanced micro devices inc	0.00	0.00	0.00	sold off	-100

AMED	amedisys inc	1.31	39,250	3,788,020	unchanged	0.00

AMGN	amgen inc	1.12	10,101	3,254,640	new

AMZN	amazon com inc	2.07	32,193	5,998,520	added	78.92

ANAB	anaptysbio inc	0.18	15,574	521,729	new

ANSS	ansys inc	1.41	12,800	4,078,460	unchanged	0.00

APLS	apellis pharmaceuticals inc	0.36	35,975	1,037,520	added	375

ARVN	arvinas inc	0.49	58,001	1,428,560	added	13.46

AUTL	autolus therapeutics plc	0.67	533,024	1,934,880	added	2.74

AVGO	broadcom inc	0.53	8,900	1,535,250	new

AXSM	axsome therapeutics inc	1.29	41,542	3,733,380	reduced	-33.2