Latest Aquilo Capital Management, LLC Stock Portfolio

About Aquilo Capital Management, LLC and 13F Hedge Fund Stock Holdings

Aquilo Capital Management, LLC is a hedge fund based in SAN FRANCISCO, CA. On 30-Mar-2023, the fund reported that it had an AUM (Regulated Assets under Management) of $442.5 Millions. In it's latest 13F Holdings report, Aquilo Capital Management, LLC reported an equity portfolio of $66.3 Millions as of 31 Dec, 2024.

The top stock holdings of Aquilo Capital Management, LLC are ARWR, BPMC, KYMR. The fund has invested 20.1% of it's portfolio in ARROWHEAD PHARMACEUTICALS IN and 17% of portfolio in BLUEPRINT MEDICINES CORP.

The fund managers got completely rid off MERUS N V (MRUS) stocks. They significantly reduced their stock positions in SUTRO BIOPHARMA INC (STRO), REGENXBIO INC (RGNX) and ARVINAS INC (ARVN). Aquilo Capital Management, LLC opened new stock positions in PROTAGONIST THERAPEUTICS INC (PTGX). The fund showed a lot of confidence in some stocks as they added substantially to PRECISION BIOSCIENCES INC (DTIL), REPARE THERAPEUTICS INC (RPTX) and BICYCLE THERAPEUTICS PLC (BCYC).

Aquilo Capital Management, LLC Annual Return Estimates Vs S&P 500

New Buys

Ticker	$ Bought
protagonist therapeutics inc	2,956,450

New stocks bought by Aquilo Capital Management, LLC

Additions

Ticker	% Inc.
precision biosciences inc	40.49
repare therapeutics inc	30.76
bicycle therapeutics plc	21.99
silence therapeutics plc	15.76
immatics n.v	12.11
blueprint medicines corp	4.01

Additions to existing portfolio by Aquilo Capital Management, LLC

Reductions

Ticker	% Reduced
sutro biopharma inc	-99.93
regenxbio inc	-62.79
arvinas inc	-15.43
kymera therapeutics inc	-12.08
arrowhead pharmaceuticals in	-11.09

Aquilo Capital Management, LLC reduced stake in above stock

Sold off

Ticker	$ Sold
merus n v	-5,888,040

Aquilo Capital Management, LLC got rid off the above stocks

Sector Distribution

Sector	%
Healthcare	91.1
Others	8.9

Market Cap. Distribution

Category	%
MID-CAP	59.8
SMALL-CAP	20.7
MICRO-CAP	10.6
UNALLOCATED	8.9

Stocks belong to which Index?

Index	%
RUSSELL 2000	79.4
Others	20.6

Top 5 Winners (%)		%

Top 5 Winners ($)		$

Top 5 Losers (%)		%
RPTX	repare therapeutics inc	-61.1 %
DTIL	precision biosciences inc	-55.6 %
BCYC	bicycle therapeutics plc	-37.7 %
ACET	adicet bio inc	-33.2 %
ARVN	arvinas inc	-17.9 %

Top 5 Losers ($)		$
RPTX	repare therapeutics inc	-2.7 M
DTIL	precision biosciences inc	-2.6 M
BCYC	bicycle therapeutics plc	-1.9 M
ARVN	arvinas inc	-1.7 M
RGNX	regenxbio inc	-1.5 M

Aquilo Capital Management, LLC Holdings Map

This heatmap illustrates the top 50 positions within the fund's portfolio.

Current Stock Holdings of Aquilo Capital Management, LLC

Last Reported on: 14 Feb, 2025

	Ticker	Namesorted descending	% Portfolio	Shares Held	$ Value	Type	% Change
	ARWR	arrowhead pharmaceuticals in	20.06	707,589	13,302,700	reduced	-11.09
Historical Trend of ARROWHEAD PHARMACEUTICALS IN Position Held By Aquilo Capital Management, LLC What % of Portfolio is ARWR?: Number of ARWR shares held: Change in No. of Shares Held:
	BPMC	blueprint medicines corp	17.05	129,600	11,303,700	added	4.01

	KYMR	kymera therapeutics inc	11.13	183,521	7,383,050	reduced	-12.08

	ARVN	arvinas inc	9.50	328,766	6,302,440	reduced	-15.43

	BCYC	bicycle therapeutics plc	4.68	221,911	3,106,750	added	21.99

	PTGX	protagonist therapeutics inc	4.46	76,592	2,956,450	new

	RGNX	regenxbio inc	4.04	346,302	2,676,910	reduced	-62.79

		immatics n.v	4.01	373,902	2,658,440	added	12.11

		silence therapeutics plc	3.81	367,214	2,526,430	added	15.76

	ACET	adicet bio inc	3.67	2,531,190	2,435,010	unchanged	0.00

	DTIL	precision biosciences inc	3.08	536,376	2,043,590	added	40.49

	RPTX	repare therapeutics inc	2.56	1,293,720	1,694,770	added	30.76

	STRO	sutro biopharma inc	0.00	498	916	reduced	-99.93

	MRUS	merus n v	0.00	0.00	0.00	sold off	-100