Latest Opaleye Management Inc. Stock Portfolio
Opaleye Management Inc. Performance:
2024 Q3: 34.07%YTD: 47.97%2023: 11.95%
Performance for 2024 Q3 is 34.07%, and YTD is 47.97%, and 2023 is 11.95%.
About Opaleye Management Inc. and 13F Hedge Fund Stock Holdings
Opaleye Management Inc. is a hedge fund based in BOSTON, MA. On 27-Mar-2023, the fund reported that it had an AUM (Regulated Assets under Management) of $422 Millions. In it's latest 13F Holdings report, Opaleye Management Inc. reported an equity portfolio of $599.6 Millions as of 30 Sep, 2024.
The top stock holdings of Opaleye Management Inc. are HROW, TGTX, OCUL. The fund has invested 29.9% of it's portfolio in HARROW HEALTH INC and 8.9% of portfolio in TG THERAPEUTICS INC.
The fund managers got completely rid off 4D MOLECULAR THERAPEUTICS INC (FDMT), IOVANCE BIOTHERAPEUTICS INC (IOVA) and INTELLIA THERAPEUTICS INC (NTLA) stocks. They significantly reduced their stock positions in CATALYST PHARMACEUTICALS INC (CPRX), REGULUS THERAPEUTICS INC (RGLS) and CYTOKINETICS INC (CYTK). Opaleye Management Inc. opened new stock positions in GINKGO BIOWORKS HOLDINGS (DNA), ZENTALIS PHARMACEUTICALS INC (ZNTL) and REZOLUTE INC (RZLT). The fund showed a lot of confidence in some stocks as they added substantially to LIQUIDIA CORPORATION (LQDA), ABCELLERA BIOLOGICS INC (ABCL) and CODEXIS INC (CDXS).
The top stock holdings of Opaleye Management Inc. are HROW, TGTX, OCUL. The fund has invested 29.9% of it's portfolio in HARROW HEALTH INC and 8.9% of portfolio in TG THERAPEUTICS INC.
The fund managers got completely rid off 4D MOLECULAR THERAPEUTICS INC (FDMT), IOVANCE BIOTHERAPEUTICS INC (IOVA) and INTELLIA THERAPEUTICS INC (NTLA) stocks. They significantly reduced their stock positions in CATALYST PHARMACEUTICALS INC (CPRX), REGULUS THERAPEUTICS INC (RGLS) and CYTOKINETICS INC (CYTK). Opaleye Management Inc. opened new stock positions in GINKGO BIOWORKS HOLDINGS (DNA), ZENTALIS PHARMACEUTICALS INC (ZNTL) and REZOLUTE INC (RZLT). The fund showed a lot of confidence in some stocks as they added substantially to LIQUIDIA CORPORATION (LQDA), ABCELLERA BIOLOGICS INC (ABCL) and CODEXIS INC (CDXS).
Opaleye Management Inc. Annual Return Estimates Vs S&P 500
Our best estimate is that Opaleye Management Inc. made a return of 34.07% in the last quarter. In trailing 12 months, it's portfolio return was 81.52%.
New Buys
| Ticker | $ Bought |
|---|---|
| ginkgo bioworks holdings | 6,684,650 |
| zentalis pharmaceuticals inc | 3,558,560 |
| rezolute inc | 2,262,830 |
| pepgen inc | 1,532,330 |
| revance therapeutics inc | 1,427,250 |
| adagio med hldgs inc | 285,273 |
New stocks bought by Opaleye Management Inc.
Additions
| Ticker | % Inc. |
|---|---|
| liquidia corporation | 422 |
| abcellera biologics inc | 300 |
| codexis inc | 153 |
| arvinas inc | 126 |
| acelyrin inc | 19.85 |
| eton pharmaceuticals inc | 16.08 |
| immunome inc | 12.24 |
| nuvalent inc | 7.93 |
Additions to existing portfolio by Opaleye Management Inc.
Reductions
| Ticker | % Reduced |
|---|---|
| catalyst pharmaceuticals inc | -82.42 |
| regulus therapeutics inc | -63.73 |
| cytokinetics inc | -62.07 |
| protara therapeutics inc | -27.04 |
| syros pharmaceuticals inc | -24.32 |
| applied therapeutics inc' | -21.43 |
| relmada therapeutics inc | -20.00 |
| lyell immunopharma inc | -16.47 |
Opaleye Management Inc. reduced stake in above stock
Sold off
| Ticker | $ Sold |
|---|---|
| lexicon pharmaceuticals inc | -3,150,000 |
| karyopharm therapeutics inc | -1,236,330 |
| ventyx biosciences inc | -2,748,900 |
| verastem inc | -2,726,700 |
| iovance biotherapeutics inc | -7,193,940 |
| savara inc | -2,881,290 |
| pmv pharmaceuticals inc | -769,500 |
| 4d molecular therapeutics inc | -7,257,290 |
Opaleye Management Inc. got rid off the above stocks
Sector Distribution
Opaleye Management Inc. has about 96.4% of it's holdings in Healthcare sector.
| Sector | % |
|---|---|
| Healthcare | 96.4 |
| Others | 3.6 |
Market Cap. Distribution
Opaleye Management Inc. has about 0% of it's portfolio invested in the large-cap and mega-cap stocks.
| Category | % |
|---|---|
| SMALL-CAP | 62.2 |
| MID-CAP | 17.7 |
| MICRO-CAP | 14.8 |
| UNALLOCATED | 4.6 |
Stocks belong to which Index?
About 81.6% of the stocks held by Opaleye Management Inc. either belong to S&P 500 or RUSSELL 2000 index.
| Index | % |
|---|---|
| RUSSELL 2000 | 81.6 |
| Others | 18.4 |
Opaleye Management Inc. Holdings Map
This heatmap illustrates the top 50 positions within the fund's portfolio.
Current Stock Holdings of Opaleye Management Inc.
Opaleye Management Inc. has 42 stocks in it's portfolio. About 72.6% of the portfolio is in top 10 stocks. SYRS proved to be the most loss making stock for the portfolio. HROW was the most profitable stock for Opaleye Management Inc. last quarter.
Last Reported on: 14 Nov, 2024| Ticker | Namesorted ascending | % Portfolio | Shares Held | $ Value | Type | % Change | Options | |
|---|---|---|---|---|---|---|---|---|
| ABCL | abcellera biologics inc | 0.35 | 800,000 | 2,080,000 | added | 300 | ||
| ALGS | aligos therapeutics inc | 0.00 | 0.00 | 0.00 | sold off | -100 | ||
| ALLK | allakos inc | 0.26 | 2,407,600 | 1,572,640 | reduced | -13.4 | ||
| APLT | applied therapeutics inc' | 1.87 | 1,320,000 | 11,220,000 | reduced | -21.43 | ||
| ARVN | arvinas inc | 5.16 | 1,255,000 | 30,910,600 | added | 126 | ||
| AVTE | aerovate therapeutics inc | 0.15 | 440,000 | 919,600 | unchanged | 0.00 | ||
| BDSX | biodesix inc | 1.16 | 3,815,000 | 6,970,700 | reduced | -5.1 | ||
| CDXS | codexis inc | 4.50 | 8,770,000 | 27,011,600 | added | 153 | ||
| CPRX | catalyst pharmaceuticals inc | 0.37 | 112,500 | 2,236,500 | reduced | -82.42 | ||
| CYTK | cytokinetics inc | 0.66 | 75,300 | 3,975,840 | reduced | -62.07 | ||
| DNA | ginkgo bioworks holdings | 1.11 | 820,202 | 6,684,650 | new | |||
| DSGN | design therapeutics inc | 0.00 | 0.00 | 0.00 | sold off | -100 | ||
| ETON | eton pharmaceuticals inc | 2.78 | 2,780,000 | 16,680,000 | added | 16.08 | ||
| EWTX | edgewise therapeutics inc | 2.33 | 522,500 | 13,945,500 | reduced | -9.91 | ||
| FDMT | 4d molecular therapeutics inc | 0.00 | 0.00 | 0.00 | sold off | -100 | ||
| FULC | fulcrum therapeutics inc | 0.00 | 0.00 | 0.00 | sold off | -100 | ||
| GOSS | gossamer bio inc | 0.70 | 8,000,000 | 4,188,930 | unchanged | 0.00 | ||
| GOSS | gossamer bio inc | 0.62 | 3,665,010 | 3,705,690 | reduced | -6.27 | ||
| HROW | harrow health inc | 29.92 | 3,990,000 | 179,390,000 | unchanged | 0.00 | ||
| IBIO | ibio inc | 0.14 | 375,000 | 832,500 | unchanged | 0.00 | ||