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Latest Paradigm Biocapital Advisors LP Stock Portfolio

Paradigm Biocapital Advisors LP Performance:
2024 Q3: 16.71%YTD: 18.94%2023: 7.59%

Performance for 2024 Q3 is 16.71%, and YTD is 18.94%, and 2023 is 7.59%.

About Paradigm Biocapital Advisors LP and 13F Hedge Fund Stock Holdings

In it's latest 13F Holdings report, Paradigm Biocapital Advisors LP reported an equity portfolio of $3 Billions as of 30 Sep, 2024.

The top stock holdings of Paradigm Biocapital Advisors LP are NUVL, ACLX, . The fund has invested 17.3% of it's portfolio in NUVALENT INC and 11.3% of portfolio in ARCELLX INC .

The fund managers got completely rid off SAREPTA THERAPEUTICS INC (SRPT), CEREVEL THERAPEUTICS HLDNG I (CERE) and ASCENDIS PHARMA A/S stocks. They significantly reduced their stock positions in COMPASS PATHWAYS PLC (CMPS), DISC MEDICINE INC and OLEMA PHARMACEUTICALS INC (OLMA). Paradigm Biocapital Advisors LP opened new stock positions in VERA THERAPEUTICS INC (VERA), MOONLAKE IMMUNOTHERAPEUTICS (MLTX) and BEIGENE LTD (BGNE). The fund showed a lot of confidence in some stocks as they added substantially to APOGEE THERAPEUTICS INC, JANUX THERAPEUTICS INC (JANX) and CULLINAN THERAPEUTICS INC (CGEM).

Paradigm Biocapital Advisors LP Annual Return Estimates Vs S&P 500

Our best estimate is that Paradigm Biocapital Advisors LP made a return of 16.71% in the last quarter. In trailing 12 months, it's portfolio return was 45.94%.

New Buys

Ticker$ Bought
vera therapeutics inc 48,480,800
moonlake immunotherapeutics 46,965,200
beigene ltd 44,977,400
spyre therapeutics inc 37,279,600
pliant therapeutics inc 34,801,300
keros therapeutics inc 30,488,900
oruka therapeutics inc 17,638,900

New stocks bought by Paradigm Biocapital Advisors LP

Additions

Ticker% Inc.
apogee therapeutics inc 112
janux therapeutics inc 53.45
cullinan therapeutics inc 50.44
erasca inc 47.15
cogent biosciences inc 27.19
merus n v 21.54
edgewise therapeutics inc 19.94
immatics n.v 14.11

Additions to existing portfolio by Paradigm Biocapital Advisors LP

Reductions

Ticker% Reduced
compass pathways plc-50.34
disc medicine inc -44.63
olema pharmaceuticals inc -30.37
argenx se -10.73
kura oncology inc -4.58
arvinas inc -4.03
viridian therapeutics inc -0.02

Paradigm Biocapital Advisors LP reduced stake in above stock

Sold off

Ticker$ Sold
vor biopharma inc -6,457,290
cerevel therapeutics hldng i-95,294,500
xenon pharmaceuticals inc -79,667,500
alx oncology hldgs inc -9,500,900
legend biotech corp -53,294,500
bridgebio pharma inc -27,596,800
sarepta therapeutics inc -149,717,000
verona pharma plc -10,426,900

Paradigm Biocapital Advisors LP got rid off the above stocks

Sector Distribution

Paradigm Biocapital Advisors LP has about 84.3% of it's holdings in Healthcare sector.

Sector%
Healthcare84.3
Others15.7

Market Cap. Distribution

Paradigm Biocapital Advisors LP has about 1.6% of it's portfolio invested in the large-cap and mega-cap stocks.

Category%
MID-CAP57.8
SMALL-CAP24.8
UNALLOCATED15.7
MEGA-CAP1.6

Stocks belong to which Index?

About 75.2% of the stocks held by Paradigm Biocapital Advisors LP either belong to S&P 500 or RUSSELL 2000 index.

Index%
RUSSELL 200075.2
Others24.8
Top 5 Winners (%)%
VRDN
viridian therapeutics inc
74.8 %
PCVX
vaxcyte inc
51.3 %
ACLX
arcellx inc
50.3 %
EWTX
edgewise therapeutics inc
46.9 %
NUVL
nuvalent inc
34.0 %
Top 5 Winners ($)$
NUVL
nuvalent inc
129.7 M
ACLX
arcellx inc
111.7 M
RVMD
revolution medicines inc
34.5 M
VRDN
viridian therapeutics inc
28.2 M
PCVX
vaxcyte inc
24.3 M
Top 5 Losers (%)%
MRUS
merus n v
-13.6 %
PLRX
pliant therapeutics inc
-10.6 %
ARVN
arvinas inc
-7.3 %
KURA
kura oncology inc
-5.0 %
CGEM
cullinan therapeutics inc
-5.0 %
Top 5 Losers ($)$
MRUS
merus n v
-19.3 M
ARVN
arvinas inc
-4.7 M
KURA
kura oncology inc
-4.6 M
PLRX
pliant therapeutics inc
-4.1 M
CGEM
cullinan therapeutics inc
-2.0 M

Paradigm Biocapital Advisors LP Holdings Map

This heatmap illustrates the top 50 positions within the fund's portfolio.

Current Stock Holdings of Paradigm Biocapital Advisors LP

Paradigm Biocapital Advisors LP has 31 stocks in it's portfolio. About 65.9% of the portfolio is in top 10 stocks. MRUS proved to be the most loss making stock for the portfolio. NUVL was the most profitable stock for Paradigm Biocapital Advisors LP last quarter.

Last Reported on: 14 Nov, 2024
TickerNamesorted ascending% PortfolioShares Held$ ValueType% ChangeOptions