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Latest Paradigm Biocapital Advisors LP Stock Portfolio

$2.61Billion– No. of Holdings #35

Paradigm Biocapital Advisors LP Performance:
2024 Q2: -4.23%YTD: 1.91%2023: 7.59%

Performance for 2024 Q2 is -4.23%, and YTD is 1.91%, and 2023 is 7.59%.

About Paradigm Biocapital Advisors LP and 13F Hedge Fund Stock Holdings

In it's latest 13F Holdings report, Paradigm Biocapital Advisors LP reported an equity portfolio of $2.6 Billions as of 30 Jun, 2024.

The top stock holdings of Paradigm Biocapital Advisors LP are NUVL, , ACLX. The fund has invested 13.3% of it's portfolio in NUVALENT INC and 8.9% of portfolio in ARGENX SE .

The fund managers got completely rid off IMMUNOCORE HLDGS PLC (IMCR), ALPINE IMMUNE SCIENCES INC (ALPN) and BICYCLE THERAPEUTICS PLC (BCYC) stocks. They significantly reduced their stock positions in VAXCYTE INC (PCVX), VIRIDIAN THERAPEUTICS INC (VRDN) and LEGEND BIOTECH CORP. Paradigm Biocapital Advisors LP opened new stock positions in MERUS N V (MRUS), JANUX THERAPEUTICS INC (JANX) and COGENT BIOSCIENCES INC (COGT). The fund showed a lot of confidence in some stocks as they added substantially to REVOLUTION MEDICINES INC (RVMD), Y-MABS THERAPEUTICS INC (YMAB) and IMMUNOVANT INC (IMVT).
Paradigm Biocapital Advisors LP Equity Portfolio Value
Last Reported on: 14 Aug, 2024

Paradigm Biocapital Advisors LP Annual Return Estimates Vs S&P 500

Our best estimate is that Paradigm Biocapital Advisors LP made a return of -4.23% in the last quarter. In trailing 12 months, it's portfolio return was 20.82%.

New Buys

Ticker$ Bought
merus n v 119,512,000
janux therapeutics inc 65,534,900
cogent biosciences inc 30,553,200
bridgebio pharma inc 27,596,800
erasca inc 17,110,000
verona pharma plc 10,426,900
alx oncology hldgs inc 9,500,900
perspective therapeutics inc9,169,330

New stocks bought by Paradigm Biocapital Advisors LP

Additions

Ticker% Inc.
revolution medicines inc 80.42
y-mabs therapeutics inc 73.29
immunovant inc 70.56
kura oncology inc 44.78
ascendis pharma a/s 30.78
immatics n.v 21.39
cullinan therapeutics inc 14.45
disc medicine inc 13.17

Additions to existing portfolio by Paradigm Biocapital Advisors LP

Reductions

Ticker% Reduced
vaxcyte inc -49.42
viridian therapeutics inc -42.43
legend biotech corp -39.29
crinetics pharmaceuticals in-19.57
xenon pharmaceuticals inc -17.77
tarsus pharmaceuticals inc -14.95
sarepta therapeutics inc -12.13
arvinas inc -6.76

Paradigm Biocapital Advisors LP reduced stake in above stock

Sold off

Ticker$ Sold
autolus therapeutics plc -40,996,600
bicycle therapeutics plc -80,844,300
caribou biosciences inc -11,167,300
alpine immune sciences inc -84,082,900
immunocore hldgs plc -116,166,000
zentalis pharmaceuticals inc-14,891,900
agios pharmaceuticals inc -11,696,000
cargo therapeutics inc -3,302,440

Paradigm Biocapital Advisors LP got rid off the above stocks

Sector Distribution

Paradigm Biocapital Advisors LP has about 78.5% of it's holdings in Healthcare sector.

Sector%
Healthcare78.5
Others21.5

Market Cap. Distribution

Paradigm Biocapital Advisors LP has about 5.7% of it's portfolio invested in the large-cap and mega-cap stocks.

Category%
MID-CAP51.9
UNALLOCATED21.5
SMALL-CAP20.2
LARGE-CAP5.7

Stocks belong to which Index?

About 64.1% of the stocks held by Paradigm Biocapital Advisors LP either belong to S&P 500 or RUSSELL 2000 index.

Index%
RUSSELL 200064.1
Others35.9
Top 5 Winners (%)%
MRUS
merus n v
26.6 %
SRPT
sarepta therapeutics inc
19.2 %
ERAS
erasca inc
12.3 %
COGT
cogent biosciences inc
11.6 %
RVMD
revolution medicines inc
11.4 %
Top 5 Winners ($)$
SRPT
sarepta therapeutics inc
26.8 M
MRUS
merus n v
25.1 M
RVMD
revolution medicines inc
20.9 M
NUVL
nuvalent inc
5.6 M
PCVX
vaxcyte inc
3.9 M
Top 5 Losers (%)%
VOR
vor biopharma inc
-57.8 %
ALXO
alx oncology hldgs inc
-54.0 %
ARVN
arvinas inc
-34.5 %
VRDN
viridian therapeutics inc
-25.4 %
TCRX
tscan therapeutics inc
-24.4 %
Top 5 Losers ($)$
ACLX
arcellx inc
-54.7 M
ARVN
arvinas inc
-37.3 M
TARS
tarsus pharmaceuticals inc
-23.9 M
VRDN
viridian therapeutics inc
-22.4 M
ALXO
alx oncology hldgs inc
-11.1 M

Paradigm Biocapital Advisors LP Holdings Map

This heatmap illustrates the top 50 positions within the fund's portfolio.

Current Stock Holdings of Paradigm Biocapital Advisors LP

Paradigm Biocapital Advisors LP has 35 stocks in it's portfolio. About 64.6% of the portfolio is in top 10 stocks. ACLX proved to be the most loss making stock for the portfolio. SRPT was the most profitable stock for Paradigm Biocapital Advisors LP last quarter.

Last Reported on: 14 Aug, 2024
TickerNamesorted ascending% PortfolioShares Held$ ValueType% ChangeOptions